A2m CLIA Kit for Rat(Rattus norvegicus) | EIAab.comA2m CLIA Kit for Rat(Rattus norvegicus)

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Index > Protein center > A2m(Gene name) > Rat

A2m (Gene name),

Alpha-2-macroglobulin (Protein name ), A2MG_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

A2m(A2m1);

Protein name:

Alpha-2-macroglobulin(Alpha-2-M);

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homotetramer; disulfide-linked.

Function:

Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

1472

Sequence:

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1472:

YEKDEFAVAK | YSAPCSTDYG | NA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00207

String:

P06238

KEGG:

rno:24153

UniGene:

Rn.225884

SMR:

P06238

KEGG:

rno:100911545

Uniprot:

P06238

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ELISA Kit for Rat Alpha-2-M

Cat.:

E1017r

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96T

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ELISA Kit for Rat Alpha-2-M

Cat.:

E1017b

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96T

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ELISA Kit for Rat Alpha-2-M

Cat.:

E1017m

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96T

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ELISA Kit for Rat Alpha-2-M

Cat.:

E1017h

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96T

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CLIA Kit for Rat Alpha-2-M

Cat.:

U1017h

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96T

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CLIA Kit for Rat Alpha-2-M

Cat.:

U1017m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Alpha-2-M

Cat.:

U1017b

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MSDS:

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Packing:

96T

CLIA Kit for Rat Alpha-2-M

Cat.:

U1017r

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Packing:

96T

Polyclonal Antibody for Rat Alpha-2-M

Cat.:

P1017Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Alpha-2-M

Cat.:

P1017Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Alpha-2-M

Cat.:

P1017Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Alpha-2-M

Protein for Rat Alpha-2-M

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Sequence of rat liver alpha 2-macroglobulin and acute phase control of its messenger RNA."
Gehring M.R. , Shiels B.R. , Northemann W. , de Bruijn M.H.L. , Kan C.-C. , Chain A.C. , Noonan D.J. , Fey G.H.
J. Biol. Chem.262:446-454(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Placenta.
3.

"Identification of the promoter sequences involved in the interleukin-6 dependent expression of the rat alpha 2-macroglobulin gene."
Kunz D. , Zimmermann R. , Heisig M. , Heinrich P.C.
Nucleic Acids Res.17:1121-1138(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-164
strain: Wistar.
tissue: Liver.
4.

"Molecular cloning of DNA complementary to rat alpha 2-macroglobulin mRNA."
Hayashida K. , Okubo H. , Noguchi M. , Yoshida H. , Kangawa K. , Matsuo H. , Sakaki Y.
J. Biol. Chem.260:14224-14229(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 178-227 AND 420-526
5.

"Sequence of rat alpha 1-macroglobulin, a broad-range proteinase inhibitor from the alpha-macroglobulin-complement family."
Eggertsen G. , Hudson G. , Shiels B. , Reed D. , Fey G.H.
Mol. Biol. Med.8:287-302(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
strain: Fischer 344.
tissue: Liver.

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